About vitamin D you can answer melanoma patients – Sohu health-霍金hawking

Vitamin D: it can be answered in melanoma patients – Sohu Sohu health tumor from American University of Texas MD Anderson cancer center Fang in the Journal of clinical oncology published research on vitamin D and melanoma, it shows that low levels of vitamin D that melanoma and poor prognosis, Professor Sondak from the tumor the center of Moffitt is reviewed on the. This study is a prospective cohort study collected plasma samples of 1042 cases of melanoma patients, detect the level of 25- hydroxyvitamin D and C reactive protein, and to evaluate the relationship between vitamin D levels in patients with essential features, CRP level, tumor staging and prognosis. Vitamin D levels were seen between 30 and 100ng mL. The results showed that vitamin D levels in patients with a median 25ng of mL, 24.6% of the patients were lower than 20ng mL, the median follow-up period was 7.1 years, slightly lower levels of vitamin D in autumn and winter, spring and autumn and autumn and winter vitamin D levels were 26.39 ng mL and 23.59 ng mL, in addition, factors associated with low level vitamin D also includes: the elderly, elevated CRP, tumor thickening, ulcer type tumors and advanced melanoma. Low levels of vitamin D indicate poor prognosis, including poor overall survival (OS), melanoma specific survival (MSS) and disease-free survival (DFS), using a recursive function of boundary value is 16 ng mL. In addition, factors associated with poor prognosis included age, men, advanced melanoma and high levels of CRP. Professor Sondak in a commentary also mentions another British cohort study published during the same period, also showed that melanoma patients with vitamin D levels lower than 20nmol L, the mortality rate is 1.52 times higher level of. So Professor Sondak explores the following questions: would it be easier to get melanoma without the sun? Certainly not. Although studies have suggested a link between vitamin D levels and melanoma, it is not enough to establish a causal link between the two. And previous studies have shown that prolonged unprotected exposure does not produce high levels of vitamin D. Do people with newly diagnosed melanoma need to detect vitamin D levels? There is still a growing controversy over the routine clinical recommendations for testing, and there is increasing evidence to support this practice. What if vitamin D levels are below normal? Oral supplements are more reliable than unprotected sun. Vitamin D supplements have side effects? Yes, may lead to hypercalcemia. Patients with oral vitamin D supplementation, especially those with high doses (> 5000IU days) should be aware of the risk of excessive exposure to vitamin D levels.相关的主题文章: